TLS and strong ciphers

I'm in the process of setting up our Verint community's production servers and want to harden them as much as possible. To that end, I've got a couple of questions:

  1. Can I disable TLS 1.0 and 1.1, or will that have an adverse affect on the software?
  2. Can I enforce strong TLS ciphers and disable weak ones, or will that have an adverse affect on the software?

Thanks

Steve